Thermo Fisher Scientific IL-35 Recombinant Rabbit Monoclonal Antibody (6H15L18)

Applications

• Western Blot (WB): 0.1–2 µg/mL
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Product Specifications

Product Specific Information

• Intact IgG appears on a non-reducing gel as an approximately 150 kDa band, and upon reduction generates ~25 kDa light chain and ~50 kDa heavy chain bands.
• Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning antibody DNA sequences from immunoreactive rabbits.
• Advantages include:
  • Improved specificity and sensitivity
  • Lot-to-lot consistency
  • Animal origin-free formulation
  • Broader immunoreactivity due to the rabbit immune repertoire

Target Information

IL-35 (Interleukin 35) is a cytokine of the IL-12 family produced by regulatory T cells. It is a dimeric protein composed of IL-12-alpha and IL-27-beta chains.
This cytokine family influences T helper cell differentiation and suppresses inflammatory responses. IL-35 promotes proliferation of regulatory T cells and reduces Th17 cell activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.