Thermo Fisher Scientific Desmoglein 2 Monoclonal Antibody (3G132)
Desmoglein 2 단백질을 인식하는 Mouse IgG1 모노클로날 항체로, WB, ICC/IF, IP에 사용 가능. A431 세포 양성 대조로 권장되며, 액상 형태로 0.1 mg/mL 농도 제공. 연구용으로만 사용 가능.
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Thermo Fisher Scientific Desmoglein 2 Monoclonal Antibody (3G132)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 20–50 µg/mL |
| Immunoprecipitation (IP) | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G132 |
| Immunogen | Full length native protein (purified) (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2261756 |
Product Specific Information
Recommended positive controls: A431 cells.
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily. These genes are clustered on chromosome 18. Desmoglein 2 has been identified as the autoantigen of pemphigus vulgaris, an autoimmune skin blistering disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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