Thermo Fisher Scientific Desmoglein 1 Monoclonal Antibody (3G131)
Desmoglein 1 단백질을 인식하는 mouse monoclonal antibody. Western blot, IHC, ICC/IF, IP 등에 사용 가능. Human 반응성, IgG1 아이소타입. Protein A 정제, 0.5 mg/mL 농도. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | 5–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3G131 |
| Immunogen | Intracellular domain of Desmoglein 1 (Human) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2230631 |
Product Specific Information
- Recommended positive controls: Differentiated keratinocytes and Desmoglein 1 transfected cells.
Target Information
Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types.
Currently, three desmoglein subfamily members have been identified, all belonging to the cadherin cell adhesion molecule superfamily.
These desmoglein gene family members are located in a cluster on chromosome 18.
Desmoglein 1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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