Thermo Fisher Scientific RAB3IP Monoclonal Antibody (OTI4B1), TrueMAB
RAB3IP 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로 Western Blot에 최적화됨. 인간, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, PBS 버퍼에 8% trehalose 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific RAB3IP Monoclonal Antibody (OTI4B1), TrueMAB
Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4B1 |
| Immunogen | Full length human recombinant protein of human RAB3IP produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RAB3IP is a guanine nucleotide exchange factor (GEF) that activates RAB8A and RAB8B by promoting GDP-to-GTP exchange. It mediates GDP release from RAB8A and RAB8B, but not from RAB3A or RAB5. RAB3IP modulates actin organization and promotes polarized vesicle transport to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42, and DNMBP, it facilitates PODXL transcytosis, apical membrane initiation, and lumenogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: CF808989_RAB3IP_Q96QF0-1_House_mouse.svg)
(이미지 파일명: CF808989_RAB3IP_Q96QF0-1_House_mouse_PDP.jpeg)
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