Thermo Fisher Scientific GTPBP2 Polyclonal Antibody
Thermo Fisher Scientific의 GTPBP2 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하는 고순도 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포 내 GTP 결합 단백질 연구에 유용합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues in Human GTPBP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.3 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719664 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Small G proteins act as molecular switches regulating various cellular processes such as nuclear transport, signal transduction, membrane trafficking, and protein synthesis.
GTPBP2 (GTP-binding protein 2) is a 602 amino acid G protein expressed in kidney, skeletal muscle, testis, brain, and thymus, but not detected in liver.
Expression of GTPBP2 is enhanced by γ-interferon stimulation in HeLa cells, THP-1 cells, and thioglycollate-elicited mouse peritoneal macrophages.
There are four isoforms of GTPBP2 expressed as a result of alternative splicing events.
GTPBP2 shares 44% sequence similarity with GTPBP1 and overlaps in expression pattern, suggesting possible genetic compensation for GTPBP1 deficiencies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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