Thermo Fisher Scientific Phospho-FER (Tyr402) Polyclonal Antibody
Phospho-FER (Tyr402) 폴리클로날 항체로, 인산화된 FER 단백질의 Tyr402 잔기를 특이적으로 검출합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 인간 및 생쥐 시료에서 반응합니다. 고순도 정제 및 안정적 보관이 가능합니다.
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Thermo Fisher Scientific Phospho-FER (Tyr402) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human FER (Accession P16591), corresponding to amino acid residues around phosphorylated Tyr402 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818072 |
Product Specific Information
Antibody detects endogenous levels of FER only when phosphorylated at Tyrosine 402.
Target Information
FER is a member of the FPS/FES family of non-receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. FER is found in both the cytoplasm and nucleus, associated with the chromatin fraction. Its ubiquitous expression and subcellular localization indicate involvement in key regulatory processes. FER has been linked to cellular signaling responses to growth factors and cytokines, and may play a biological role in leukocyte recruitment during the innate immune response.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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