Thermo Fisher Scientific 5T4 Recombinant Rabbit Monoclonal Antibody (SU34-05)
5T4 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot에 최적화됨. 사람, 마우스, 랫트 시료 반응성. 높은 특이성과 일관성 제공. 단백질 A로 정제된 액상 형태로, 4°C 또는 -20°C 보관 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SU34-05 |
| Immunogen | Synthetic peptide within Human 5T4 aa 381–420 (UniProt ID: Q13641-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2801549 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and expressed to generate specific recombinant antibodies.
These antibodies offer:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to the rabbit immune repertoire
Target Information
The 5T4 gene encodes a leucine-rich transmembrane glycoprotein potentially involved in cell adhesion. It is an oncofetal antigen specific to trophoblast cells and is highly expressed in many tumor cells in adults. Expression correlates with poor clinical outcomes in various cancers. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.
(Information provided by RefSeq, Oct 2009)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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