Thermo Fisher Scientific SCP2/NLTP Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Target Information

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from two independently regulated promoters.
The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the two proteins sharing a common C-terminus.
Evidence suggests that the SCPx protein is a peroxisome-associated thiolase involved in oxidation of branched chain fatty acids, while the SCP2 protein functions as an intracellular lipid transfer protein.
This gene is highly expressed in organs involved in lipid metabolism and may play a role in Zellweger syndrome, where cells are deficient in peroxisomes and have impaired bile acid synthesis.
Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.