Thermo Fisher Scientific GLT-1 Recombinant Rabbit Monoclonal Antibody (9H9L17)
GLT-1 단백질을 인식하는 Thermo Fisher의 재조합 토끼 단일클론 항체. WB, IHC, ICC에 사용 가능하며 높은 특이성과 일관성 제공. 인간, 생쥐, 랫트 반응성. 단백질 A로 정제된 액상 항체로 연구용으로 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 9H9L17 |
| Immunogen | Peptides corresponding to Human SLC1A2 (aa 5–20, 148–166) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2633044 |
Product Specific Information
This antibody is predicted to react with Monkey, Rabbit, and Sheep.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies include:
- Better specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulations
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. This membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system.
Glutamate clearance is essential for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors.
Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS).
Alternatively spliced transcript variants of this gene have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: 701988_GLT-1_P43004-1_Rabbit.svg, 701988_GLT-1_P43004-1_Rabbit_PDP.jpeg)
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