Thermo Fisher Scientific ICOS Monoclonal Antibody (OTI3E8)
Human ICOS 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Flow Cytometry에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 세포 신호전달 및 면역반응 연구용으로 적합합니다.
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Applications
- Flow Cytometry (Flow): 1:100–1:400 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E8 |
| Immunogen | Full length human recombinant protein of human ICOS (NP_036224) produced in 293F cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ICOS (CD278) encodes a protein belonging to the CD28 and CTLA-4 cell-surface receptor family. It functions as a homodimer and plays a crucial role in cell-cell signaling, immune responses, and regulation of cell proliferation.
Mutations or dysregulation of ICOS have been associated with disorders such as Immunodeficiency, Common Variable, 1 and Common Variable Immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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