Thermo Fisher Scientific alpha Galactosidase Recombinant Rabbit Monoclonal Antibody (23GB5545)
Recombinant rabbit monoclonal antibody specific for human alpha-Galactosidase. Validated for Western blot and flow cytometry. High purity (affinity chromatography), liquid form with 1.23 mg/mL concentration. Suitable for research on Fabry disease mecha...
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Flow Cytometry (Flow)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293F |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 23GB5545 |
| Immunogen | A synthesized peptide derived from human Galactosidase alpha (100–150AA) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.23 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyzes the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. The enzyme primarily hydrolyzes ceramide trihexoside and can catalyze the hydrolysis of melibiose into galactose and glucose. Mutations in this gene can impair enzyme synthesis and stability, leading to Fabry disease — a lysosomal storage disorder caused by defective catabolism of alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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