Thermo Fisher Scientific GCLM Recombinant Rabbit Monoclonal Antibody (23GB5535)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

-

Flow Cytometry (Flow)

1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293F

Class

Recombinant Monoclonal

Type

Antibody

Clone

23GB5535

Immunogen

A synthesized peptide derived from human GCLM (65-100AA). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GCLM,uniProtId:P48507-1,ncbiNodeId:9606,antigenRange:65-100,antigenLength:274,antigenImageFileName:MA5-53894_GCLM_P48507-1_Rabbit.svg,antigenImageFileNamePDP:MA5-53894_GCLM_P48507-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.18 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Target Information

Gamma-glutamylcysteine synthetase (gamma-GCS) is the rate limiting enzyme for glutathione (L-gamma-glutamyl-L-cysteinylglycine, GSH) synthesis. GSH is ubiquitous in mammalian cells as a vital intra- and extracellular protective antioxidant. Gamma-GCS is a heterodimer of a heavy catalytic subunit and a light regulatory subunit that is responsive to inflammation, phenolic ntioxidants, heat shock, oxidants and cytokines.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.