Thermo Fisher Scientific Gemin 4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-350 of human GEMIN4 (NP_0565362) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Gemin 4,uniProtId:P57678-1,ncbiNodeId:9606,antigenRange:50-350,antigenLength:1058,antigenImageFileName:PA5-88031_Gemin_4_P57678-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88031_Gemin_4_P57678-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.29 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804602

Product Specific Information

Immunogen sequence: LREISSAAAH SQPFAWKKKA LIIIWAKVLQ PHPVTPSDTE TRWQEDLFFS VGNMIPTINH TILFELLKSL EASGLFIQLL MALPTTICHA ELERFLEHVT VDTSAEDVAF FLDVWWEVMK HKGHPQDPLL SQFSAMAHKY LPALDEFPHP PKRLRSDPDA CPTMPLLAML LRGLTQIQSR ILGPGRKCCA LANLADMLTV FALTEDDPQE VSATVYLDKL ATVISVWNSD TQNPYHQQAL AEKVKEAERD VSLTSLAKLP SETIFVGCEF LHHLLREWGE ELQAVLRSSQ GTSYDSYRLC D; Positive Samples: HeLa, MCF-7, SH-SY5Y, Jurkat, Mouse brain, Mouse kidney, Mouse liver; Cellular Location: Cytoplasm, Nucleus, gem, nucleolus

Target Information

The product of this gene is part of a large complex localized to the cytoplasm, nucleoli, and to discrete nuclear bodies called Gemini bodies. The complex functions in spliceosomal snRNP assembly in the cytoplasm, and regenerates spliceosomes required for pre-mRNA splicing in the nucleus. The encoded protein directly interacts with a DEAD box protein and several spliceosome core proteins. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.