Thermo Fisher Scientific mGluR5 (extracellular) Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
The reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
For longer storage, aliquot and keep at -20°C. Avoid multiple freeze-thaw cycles.
Centrifuge all antibody preparations before use (10,000 × g, 5 min).

Target Information

GRK1 is a member of the G protein-coupled receptor kinase (GRK) subfamily of the Serine/Threonine kinase family.
It phosphorylates rhodopsin and initiates its deactivation. Phosphorylation promotes arrestin binding, which removes the receptor from the G-protein and terminates signaling.
GRK1 is farnesylated to promote membrane association and is inhibited by recoverin, a calcium-binding protein.
Diseases associated with GRK1 dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.