Thermo Fisher Scientific mGluR5 (extracellular) Polyclonal Antibody
mGluR5 수용체의 세포외 도메인을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow Cytometry에 적합합니다. Antigen affinity chromatography로 정제되었으며, Lyophilized 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- AGC-007-xxxxx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific mGluR5 (extracellular) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 5 µg |
| Flow Cytometry (Flow) | 5 µg |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | EGFAQENSKYNKTC, corresponding to amino acids 367–380 of rat mGluR5 (Extracellular, N-terminus) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.75 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 1% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Reconstitution: Add 25 µL, 50 µL, or 0.2 mL of double distilled water (DDW), depending on the sample size.
The antibody ships as a lyophilized powder at room temperature. Upon arrival, store at -20°C.
The reconstituted solution can be stored at 4°C, protected from light, for up to 1 week.
For longer storage, aliquot and keep at -20°C. Avoid multiple freeze-thaw cycles.
Centrifuge all antibody preparations before use (10,000 × g, 5 min).
Target Information
GRK1 is a member of the G protein-coupled receptor kinase (GRK) subfamily of the Serine/Threonine kinase family.
It phosphorylates rhodopsin and initiates its deactivation. Phosphorylation promotes arrestin binding, which removes the receptor from the G-protein and terminates signaling.
GRK1 is farnesylated to promote membrane association and is inhibited by recoverin, a calcium-binding protein.
Diseases associated with GRK1 dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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