Thermo Fisher Scientific PKC mu Recombinant Rabbit Monoclonal Antibody (ARC1919)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1919

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PKC mu (Q15139) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PKC mu,uniProtId:O94806-1,ncbiNodeId:9606,antigenRange:200-300,antigenLength:890,antigenImageFileName:MA5-38046_PKC_mu_O94806-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38046_PKC_mu_O94806-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.25 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2897964

Product Specific Information

Positive Samples: HeLa, HT-29, U-87MG, Mouse lung, Mouse testis, Mouse kidney, Rat lung, Rat testis, Rat kidney

Immunogen sequence: RRRRLSNVSL TGVSTIRTSS AELSTSAPDE PLLQKSPSES FIGREKRSNS QSYIGRPIHL DKILMSKVKV PHTFVIHSYT RPTVCQYCKK LLKGLFRQGL Q

Target Information

The PKC family of serine/threonine kinases, including PRKCN (PKD3), is activated intracellularly by signal transduction pathways. In humans, at least 12 different PKC polypeptides have been identified. These isoforms differ in primary structure, tissue distribution, subcellular localization, mode of action in vitro, response to extracellular signals, and substrate specificity. PKC alpha, beta I, beta II and gamma form the conventional family; their activities are Ca2+- and phospholipid-dependent. PKC mu activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.