Thermo Fisher Scientific NUP153 Recombinant Rabbit Monoclonal Antibody (ARC1922)
NUP153 단백질을 인식하는 재조합 토끼 단클론 항체로 Western blot, IHC, ICC, ELISA에 적합합니다. HEK293 세포에서 발현되었으며, Human, Mouse, Rat 시료에 반응합니다. 고순도 친화 크로마토그래피 정제 제품으로, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1922 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human NUP153 (UniProt ID: P49790) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897966 |
Product Specific Information
- Positive Samples: HeLa, K-562, Mouse testis
- Immunogen Sequence:
MASGAGGVGG GGGGKIRTRR CHQGPIKPYQ QGRQQHQGIL SRVTESVKNI VPGWLQRYFN KNEDVCSCST DTSEVPRWPE NKEDHLVYAD EESSNITDGR
Target Information
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They consist of at least 100 distinct polypeptide subunits, many belonging to the nucleoporin family. Nucleoporins are glycoproteins located in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented toward the cytoplasm.
The NUP153 protein has three distinct domains:
- N-terminal region – contains pore targeting and RNA-binding domains
- Central region – contains multiple zinc finger motifs
- C-terminal region – contains multiple XFXFG repeats
Alternative splicing results in multiple transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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