Thermo Fisher Scientific FNTB Recombinant Rabbit Monoclonal Antibody (ARC1923)
Thermo Fisher Scientific의 FNTB Recombinant Rabbit Monoclonal Antibody (ARC1923)는 인간 및 랫트 시료에 반응하는 고감도 항체로, WB, IHC, ELISA에 적합합니다. HEK293 발현 시스템에서 생산된 재조합 단일클론 항체이며, 높은 순도(1.3 mg/mL)와 안정성을 제공합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1923 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human FNTB (UniProt ID: P49356) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS (pH 7.3), 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897967 |
Product Specific Information
- Positive Samples: HeLa, 293T, A-431, Rat brain
- Immunogen sequence:
MASPSSFTYY CPPSSSPVWS EPLYSLRPEH ARERLQDDSV ETVTSIEQAK VEEKIQEVFS SYKFNHLVPR LVLQREKHFH YLKRGLRQLT DAYECLDASR
Target Information
Eukaryotic cells contain three types of prenyltransferases that attach either a farnesyl (15 carbons) or a geranylgeranyl (20 carbons) group via thioether linkage to C-terminal cysteine residues of various proteins. These posttranslational modifications enable membrane localization of proteins lacking transmembrane domains.
CAAX farnesyltransferase (FTase) attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus in proteins ending with the CAAX box (C = cysteine, A = aliphatic amino acid, X = methionine or serine).
The FNTB gene, encoding the beta subunit of CAAX farnesyltransferase, is mapped to chromosome 14q23–q24 by Southern blot hybridization and PCR analyses.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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