Thermo Fisher Scientific DLL3 Recombinant Human Monoclonal Antibody (7B7)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1:50-1:200

-

ELISA (ELISA)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Human / IgG1

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7B7

Immunogen

Recombinant Human DLL3 protein if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DLL3,uniProtId:Q9NYJ7-1,ncbiNodeId:9606,antigenRange:1-618,antigenLength:618,antigenImageFileName:MA5-43156_DLL3_Q9NYJ7-1_Human.svg,antigenImageFileNamePDP:MA5-43156_DLL3_Q9NYJ7-1_Human_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

Shipping conditions

Wet ice

RRID

AB_2912292

Product Specific Information

Antibody tested in Indirect ELISA

Target Information

Delta-like protein 3 (DLL3) is a ligand for the Notch signaling pathway. It inhibits primary neurogenesis. DLL3 plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Defects in DLL3 are the cause of Spondylocostal dysostosis autosomal recessive type 1 (SCDO1). Mutations in DLL3 gene cause truncal shortening relative to their limbs, which leads to abdominal protrusion, abnormal spinal curvature and sometimes a plagiocephaly-torticollis sequence. It may be required to divert neurons along a specific differentiation pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.