Thermo Fisher Scientific CD185 (CXCR5) Monoclonal Antibody (MU5UBEE), PE-Cyanine7, eBioscience
CD185(CXCR5) 단일클론 항체(MU5UBEE)는 인간 및 비인간 영장류 반응성을 가지며, PE-Cyanine7 형광으로 결합된 Flow Cytometry용 항체입니다. 림프구 이동 및 여포성 T세포 표지 연구에 적합하며, 광민감성이 있어 암조건 보관이 필요합니다.
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Thermo Fisher Scientific CD185 (CXCR5) Monoclonal Antibody (MU5UBEE), PE-Cyanine7, eBioscience™
Applications and Tested Dilution
- Application: Flow Cytometry (Flow)
- Tested Dilution: 5 µL (0.06 µg)/test
- View 13 Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate, Rhesus monkey |
| Published Species | Human, Mouse, Non-human primate, Rhesus monkey |
| Host / Isotype | Mouse / IgG2b, kappa |
| Recommended Isotype Control | Mouse IgG2b kappa Isotype Control (eBMG2b), PE-Cyanine7, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MU5UBEE |
| Immunogen | N-terminal extracellular domain of CXCR5 |
| Conjugate | PE-Cyanine7 |
| Excitation / Emission Max | 569 / 780 nm |
| Form | Liquid |
| Concentration | 5 µL/test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2573539 |
Additional Available Formats
- Unconjugated
- Alexa Fluor 532, 700
- APC, Biotin
- Brilliant UV (395–805 series)
- Brilliant Violet (421–786 series)
- eFluor 450, FITC
- NovaFluor (Blue, Red, UV, Violet, Yellow series)
- PE, PE-Cyanine5, PE-eFluor 610
- PerCP-eFluor 710
- Super Bright (436–702 series)
- Request Custom Conjugation
Product Specific Information
The MU5UBEE monoclonal antibody reacts with human and non-human primate CD185 (CXCR5/BLR1), a seven-transmembrane G protein-coupled receptor originally identified in Burkitt’s lymphoma.
CD185 is expressed on B cells, CD4⁺ T cells, and memory (CD45RO⁺) T cells, playing a key role in lymphocyte trafficking and follicular helper T cell identification.
- Applications Reported: Flow cytometric analysis
- Applications Tested: Pre-titrated for flow cytometry at 5 µL (0.06 µg) per test (100 µL final volume)
- Light Sensitivity: Tandem dye is photo-sensitive; protect from light
- Fixation: Compatible with IC Fixation Buffer (Product #00-8222) or 1-step Fix/Lyse Solution (Product #00-5333) for up to 3 days at 4°C in dark
- Excitation: 488–561 nm
- Emission: 775 nm
- Laser Compatibility: Blue, Green, Yellow-Green lasers
- Filtration: 0.2 µm post-manufacturing filtered
Target Information
CXCR5 (C-X-C Chemokine Receptor Type 5, CD185)
Also known as Burkitt lymphoma receptor 1 (BLR1), CXCR5 is a G protein-coupled receptor involved in B cell migration and lymphocyte trafficking.
Expressed in Burkitt’s lymphoma, lymph nodes, spleen, and various tissues, CXCR5 plays a vital role in immune cell localization and follicular T cell function.
GPCRs, including CXCR5, are major signaling molecules with significant pharmacological implications.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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