Thermo Fisher Scientific MAGED2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MAGED2 protein. Validated for WB, IHC, IHC-P, and IP applications. Supplied as an unconjugated liquid form at 0.20 mg/mL. Recommended storage at 4°C with 1-year shelf life. For research use only.
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Thermo Fisher Scientific MAGED2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 50 and 100 of human melanoma antigen family D, 2 (MAGED2; UniProt ID: Q9UNF1-1; Antigen length: 606 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
This gene is a member of the MAGED gene family clustered on chromosome Xp11. Located in Xp11.2, a region associated with X-linked intellectual disability (XLID). Mutations in MAGED2 cause transient antenatal Bartter’s syndrome. It may also be implicated in cancers such as breast cancer and melanoma. The encoded protein relocates from the cytoplasm to the nucleoplasm during interphase and after nucleolar stress, suggesting a role in cell cycle regulation. Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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