Thermo Fisher Scientific MAGED2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human MAGED2 for WB, IHC, and IP applications. Recognizes residues 1–50 of MAGED2 protein. Supplied as liquid, unconjugated form at 0.20 mg/mL. Recommended storage at 4°C; shelf life 1 year. For research use only.
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Thermo Fisher Scientific MAGED2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human melanoma antigen family D, 2 (MAGED2, UniProt ID: Q9UNF1-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
Target Information
This gene belongs to the MAGED gene family, clustered on chromosome Xp11. The MAGED2 gene is located at Xp11.2, a region associated with X-linked intellectual disability (XLID). Mutations in MAGED2 cause transient antenatal Bartter’s syndrome. MAGED2 may also be involved in various cancers, including breast cancer and melanoma. The encoded protein relocates from the cytoplasm to the nucleoplasm during interphase and after nucleolar stress, suggesting a role in cell cycle regulation. Alternative splicing produces multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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