Thermo Fisher Scientific CRSP2/DRIP150 Polyclonal Antibody
CRSP2/DRIP150 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human cofactor required for Sp1 transcriptional activation, subunit 2 (vitamin D receptor-interacting protein complex component DRIP150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
The activation of gene transcription is a multistep process triggered by factors recognizing transcriptional enhancer sites in DNA. These factors cooperate with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
The encoded protein is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. It also participates in other multisubunit complexes such as thyroid hormone receptor-associated proteins (TRAP), facilitating TR function on DNA templates.
This protein contains a bipartite nuclear localization signal and is known to escape chromosome X-inactivation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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