Thermo Fisher Scientific Phospho-EpoR (Tyr454, Tyr456) Recombinant Superclonal Antibody (3HCLC)
인간 EPO 수용체의 Tyr454 및 Tyr456 인산화 부위를 인식하는 재조합 Superclonal™ 항체입니다. WB 및 ICC/IF에 사용 가능하며, 높은 특이성과 감도를 제공합니다. 일관된 로트 간 재현성을 보장하며 단백질 A로 정제된 액상 형태입니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 3HCLC |
| Immunogen | Phosphorylation of the human EPO Receptor at Tyr454 and Tyr456 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532724 |
Product Specific Information
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple different recombinant monoclonal antibodies, providing both polyclonal-like sensitivity and monoclonal-like specificity, while ensuring batch-to-batch consistency.
Each Superclonal™ antibody contains a defined mixture of light and heavy chains, eliminating biological variability typical of polyclonal production.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. The product and performance remain unchanged.
Target Information
EpoR encodes the erythropoietin receptor, a member of the cytokine receptor family. Binding of erythropoietin activates Jak2 tyrosine kinase, triggering intracellular signaling pathways such as Ras/MAPK, PI3K, and STAT transcription factors.
Activated EpoR supports erythroid cell survival. Mutations in this gene may cause erythroleukemia or familial erythrocytosis, and dysregulation can influence tumor growth. Multiple transcript variants exist due to alternative splicing.
Diseases associated with EPOR include Erythrocytosis, Familial 1 and Erythroleukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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