Thermo Fisher Scientific PIM1 Recombinant Superclonal Antibody (19HCLC)
PIM1 단백질을 표적하는 Thermo Fisher의 Recombinant Superclonal 항체. 다중 에피토프 인식으로 높은 감도와 일관성 제공. WB, IHC, ICC 등 다양한 응용에 적합. 인간 및 마우스 반응성, Expi293 발현 시스템 기반.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 | - |
| Immunocytochemistry (ICC/IF) | 1:100 | 1 publication |
| in situ PLA (PLA) | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 19HCLC |
| Immunogen | Peptide corresponding to amino acids 115–130 of human PIM-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532727 |
Product Specific Information
This antibody is predicted to react with bovine, canine, equine, feline, non-human primate, mouse, rabbit, ovine, and porcine based on sequence homology.
Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They combine multiple different recombinant monoclonal antibodies, providing both the sensitivity of polyclonal antibodies and the specificity of monoclonal antibodies, with the consistency of recombinant production.
While functionally similar to polyclonal antibodies—recognizing multiple epitope sites and offering high detection sensitivity for low-abundance targets—Superclonal™ antibodies have a defined mixture of light and heavy chains, ensuring reproducibility across lots and eliminating biological variability.
Note: Formerly termed “Recombinant polyclonal antibody,” now rebranded as “Recombinant Superclonal™ antibody.” The product and performance remain unchanged.
Target Information
The proto-oncogene PIM1 is upregulated in prostate cancer and belongs to the Serine/Threonine protein kinase family. It plays a role in signal transduction in blood cells and may influence chromatin structure or silencing by phosphorylating HP1 gamma/CBX3. PIM1 is primarily expressed in hematopoietic and germ line cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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