Thermo Fisher Scientific CD155 Monoclonal Antibody (2H7CD155), APC, eBioscience
CD155 단백질을 인식하는 2H7CD155 단클론 항체로, APC 형광체가 결합된 제품입니다. 인간 시료에서 Flow Cytometry 분석에 최적화되어 있으며, 5 µL/test로 사용됩니다. CD155은 poliovirus receptor로 알려져 있으며, 세포 부착 및 NK 세포 활성 연구에 활용됩니다.
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Thermo Fisher Scientific CD155 Monoclonal Antibody (2H7CD155), APC, eBioscience
Applications
- Flow Cytometry (Flow)
Tested Dilution: 5 µL (0.25 µg)/test
Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), APC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2H7CD155 |
| Conjugate | APC |
| Excitation/Emission Max | 651 / 660 nm |
| Form | Liquid |
| Concentration | 5 µL/Test |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724062 |
Additional Formats
- FITC
- PE
- PE-Cyanine7
- PerCP-eFluor 710
- Super Bright 436
- Request custom conjugation available
Product Specific Information
The monoclonal antibody 2H7CD155 recognizes CD155, also known as the poliovirus receptor.
CD155 is a member of the Ig superfamily with four isoforms; only the alpha and delta forms are expressed on the membrane of monocytes, prostate cancer cells, and neurectodermal or monocytic tumor cell lines.
It is also found during mid-gastrulation in embryonic development. CD155 participates in adhesion through interaction with vitronectin and plays a role in NK cell-mediated killing of tumor cells.
Ligands for CD155 include CD226 and CD96.
Blocking of CD155 is under therapeutic investigation for prevention of poliovirus variants.
Applications Reported:
This antibody is suitable for flow cytometric analysis.
Applications Tested:
Pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells or the U937 human tumor cell line.
Use at 5 µL (0.25 µg) per test in a final volume of 100 µL.
Cell number can range from 10⁵ to 10⁸ cells/test.
Excitation: 633–647 nm
Emission: 660 nm
Laser: Red Laser
Target Information
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily.
Its external domain mediates cell attachment to vitronectin, while the intracellular domain interacts with dynein light chain Tctex-1/DYNLT1.
This gene is specific to the primate lineage and serves as a cellular receptor for poliovirus in the initial step of viral replication.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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