Thermo Fisher Scientific Phospho-4EBP1 (Thr37, Thr46) Recombinant Rabbit Monoclonal Antibody (4EB1T37T46-A5), FITC
Phospho-4EBP1 (Thr37, Thr46) 인산화 부위를 인식하는 FITC 표지 재조합 토끼 단일클론 항체. 인간, 마우스, 랫트 반응성. Flow Cytometry에 최적화. Protein A/G 정제 및 BSA 함유 PBS buffer에 보관. 4°C 암소 보관 권장.
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Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4EB1T37T46-A5 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.20% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896872 |
Additional Formats
- Unconjugated (MA5-36935)
- APC (MA5-36938)
- PE (MA5-36936)
- Custom conjugation available upon request
Target Information
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs. Interaction with eIF4E inhibits complex assembly and represses translation. Phosphorylation in response to signals such as UV irradiation and insulin causes dissociation from eIF4E and activation of mRNA translation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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