Thermo Fisher Scientific ATOH1 Monoclonal Antibody (1B12)
ATOH1 단백질을 인식하는 Mouse Monoclonal 항체로 Western Blot, ICC/IF, ELISA에 사용 가능. Human 시료에 반응하며, Affinity chromatography로 정제됨. PBS buffer에 보존, -20°C에서 보관. 연구용으로 적합.
- 카탈로그번호
- H00000474-M01
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B12 |
| Immunogen | ATOH1 (NP_005163.1, 266–354 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
PTPPGSCRTR FSAPASAGGY SVQLDALHFS TFEDSALTAM MAQKNLSPSL PGSILQPVQE ENSKTSPRSH RSDGEFSPHS HYSDSDEAS
Target Information
The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system.
Mammalian atonal homolog 1 (MATH-1), also known as ATOH1, ATH1, or HATH-1, is a 351 amino acid transcription factor with a bHLH domain homologous to the Drosophila atonal product.
In mice, MATH-1 expression begins around embryonic day 9.5, initially localizing to cranial ganglions and the dorsal part of the central nervous system. By day 18, expression becomes restricted to the external granular layer of the cerebellum and is undetectable in adults.
MATH-1 is believed to play a role in neural cell differentiation by activating E box-dependent transcription.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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