Thermo Fisher Scientific ATOH1 Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MSRLLHAEEW AEVKELGDHH RQPQPHHLPQ PPPPPQPPAT LQAREHPVYP PELSLLDSTD PRAWLAPTLQ GICTARAAQY LLHSPELGAS EAAAPRDEVD GRGELVRRSS GGASSSKSPG PVKVREQLCK LKGGVVVDEL GCSRQRAPSS KQVNGVQKQR RLAANARERR RMHGLNHAFD QLRNVIPSFN NDKKLSKYET LQMAQIYINA LSELLQTPSG GEQPPPPPAS CKSDHHHLRT AASYEGGAGN ATAAGAQQAS GGSQRPTPPG SCRTRFSAPA SAGGYSVQLD ALHFSTFEDS ALTAMMAQKN LSPSLPGSIL QPVQEENSKT SPRSHRSDGE FSPHSHYSDS DEAS

Target Information

The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains essential for nervous system development. Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid HLH transcription factor homologous to the Drosophila proneural gene atonal.
In mice, MATH-1 expression begins by embryonic day 9.5 in cranial ganglions and the dorsal central nervous system, later localizing to the external granular layer of the cerebellum by day 18 and disappearing in adults.
MATH-1 may play a role in neural cell differentiation via activation of E box-dependent transcription.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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