Thermo Fisher Scientific ATOH1 Monoclonal Antibody (3E2)
ATOH1 단백질을 인식하는 Mouse monoclonal antibody(3E2). Western blot, ICC/IF, ELISA에 최적화되어 있으며 인간 시료에 반응. PBS buffer, no preservative, -20°C 보관. 연구용으로만 사용.
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- H00000474-M05
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3E2 |
| Immunogen | ATOH1 (NP_005163.1, 266–354 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
PTPPGSCRTR FSAPASAGGY SVQLDALHFS TFEDSALTAM MAQKNLSPSL PGSILQPVQE ENSKTSPRSH RSDGEFSPHS HYSDSDEAS
Target Information
The Drosophila atonal gene produces a protein with basic helix-loop-helix (bHLH) domains that plays an essential role in the development of the Drosophila nervous system.
Mammalian atonal homolog 1 (MATH-1), also known as Atoh1, Ath1, or HATH-1, is a 351 amino acid protein with an atonal-related basic HLH domain.
In mice, MATH-1 expression begins around embryonic day 9.5, initially localizing to cranial ganglia and the dorsal part of the central nervous system. Expression becomes restricted to the external granular layer of the cerebellum by day 18 and is undetectable in the adult nervous system.
MATH-1 may play a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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