Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Polyclonal Antibody
SARS-CoV-2 Spike Protein S1 서브유닛을 인식하는 Rabbit Polyclonal 항체. SARS-CoV 및 MERS-CoV와 교차 반응 없음. WB, ICC/IF, ELISA에 적합. 0.5 mg/mL 농도의 액상 형태로 제공되며, 연구용으로만 사용 가능.
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- PA5114447
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Applications 및 Tested Dilution
| Application | Tested Dilution | 참고 문헌 |
|---|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 | - |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminal region of SARS-CoV-2 (COVID-19) spike (S1). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2890578 |
Product Specific Information
This antibody detects SARS-CoV-2 spike protein (S1 subunit), but does not cross-react with SARS-CoV or MERS-CoV spike proteins based on internal testing.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus that causes illnesses ranging from mild cold symptoms to severe respiratory distress and death.
The Spike Protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus.
S1 contains a receptor-binding domain (RBD) that specifically binds to angiotensin-converting enzyme 2 (ACE2) on target cells.
Spike and nucleocapsid proteins can be detected in infected cell culture supernatants using antisera from SARS patients.
Variations in Spike proteins contribute to CoV diversity, influencing receptor interactions and viral fusion mechanisms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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