Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Polyclonal Antibody
SARS-CoV-2 스파이크 단백질 S1 서브유닛을 인식하는 토끼 폴리클로날 항체입니다. WB, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. SARS-CoV 및 MERS-CoV와 교차 반응하지 않습니다. 항원 친화 크로마토그래피로 정제된 고품질 연구용 항체입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of SARS-CoV-2 (COVID-19) spike (S1). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2890577 |
Product Specific Information
This antibody detects SARS-CoV-2 spike protein (S1 subunit), but does not cross-react with SARS-CoV or MERS-CoV spike proteins based on internal testing.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus causing illnesses from mild cold-like symptoms to severe respiratory distress and death.
The Spike Protein consists of S1 and S2 domains and serves as the main surface antigen of the coronavirus.
The glycosylated Spike protein and nucleocapsid protein can be detected in infected cell culture supernatants with antisera from SARS patients.
S1 contains the receptor-binding domain (RBD) that specifically binds to ACE2, the receptor on target cells.
CoV diversity is reflected in the variable Spike proteins, which have evolved to differ in receptor interactions and responses to environmental triggers of virus-cell membrane fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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