Thermo Fisher Scientific MPS1 Monoclonal Antibody (4A12)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA5-15522 targets MPS1 in indirect ELISA and IHC applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of MPS1 expressed in E. coli.
MA5-15522 detects MPS1, which has a predicted molecular weight of approximately 95 kDa.

Target Information

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins.
This gene encodes a ribosomal protein that is a component of the 40S subunit and belongs to the S27E family of ribosomal proteins. It contains a C4-type zinc finger domain capable of binding zinc and nucleic acids.
The protein is primarily located in the cytoplasm as a ribosomal component but has also been detected in the nucleus.
Studies in rat indicate that ribosomal protein S27 is located near ribosomal protein S18 in the 40S subunit and is covalently linked to translation initiation factor eIF3.
As is typical for genes encoding ribosomal proteins, multiple processed pseudogenes of this gene are dispersed throughout the genome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.