Thermo Fisher Scientific CD18 Monoclonal Antibody (10E12)
CD18 단백질을 표적하는 Mouse IgG2b 단클론 항체로, 인간 및 생쥐 시료에 반응합니다. ELISA와 면역형광(ICC/IF)에 적합하며, 세포 부착 및 신호전달 연구에 활용됩니다. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 보관 권장.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10E12 |
| Immunogen | Purified recombinant fragment of CD18 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not Determined |
| Storage Buffer | Ascites |
| Contains | 0.03% Sodium Azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet Ice |
| RRID | AB_10984783 |
Product Specific Information
MA5-15517 targets CD18 in indirect ELISA and IF applications, showing reactivity with human and mouse samples.
The immunogen is a purified recombinant fragment of CD18 expressed in E. coli.
MA5-15517 detects CD18 with a predicted molecular weight of approximately 85 kDa.
Target Information
CD18 (integrin beta 2 subunit) is a 90 kDa type I transmembrane protein expressed on all leukocytes.
It forms heterodimers with CD11 molecules (CD11a–d) to constitute leukocyte β2 integrins:
- αLβ2 (CD11a/CD18, LFA-1)
- αMβ2 (CD11b/CD18, Mac-1, CR3)
- αXβ2 (CD11c/CD18)
- αDβ2 (CD11d/CD18)
These integrins are essential for proper leukocyte migration and intercellular adhesion.
Deficiency or reduction in CD18 expression leads to leukocyte adhesion deficiency type I (LAD1) and may cause psoriasiform skin disease.
CD18 is also a receptor for Mannheimia haemolytica leukotoxin, mediating leukotoxin-induced cytolysis.
Two transcript variants encoding the CD18 protein have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific MPS1 Monoclonal Antibody (4A12)
678,400원
Thermo Fisher Scientific
Thermo Fisher Scientific MUSK Monoclonal Antibody (10A4)
742,900원
Thermo Fisher Scientific
Thermo Fisher Scientific CD18 Monoclonal Antibody (10E12)
678,400원
Thermo Fisher Scientific
Thermo Fisher Scientific ISL1 Monoclonal Antibody (1B1)
665,700원
Thermo Fisher Scientific
Thermo Fisher Scientific ISL1 Monoclonal Antibody (1H9)
742,900원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|