Thermo Fisher Scientific FIBB Monoclonal Antibody (1F9)
인간 FGB 단백질을 인식하는 마우스 단클론 항체로, Western blot과 ELISA에 최적화되어 있습니다. 비결합형 액상 형태이며, 단기 보관은 4°C, 장기 보관은 -20°C에서 수행합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1F9 |
| Immunogen | Purified recombinant fragment of human FGB (aa30–300) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10983765 |
Product Specific Information
MA5-15519 targets FGB in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of human FGB (amino acids 30–300) expressed in E. coli.
MA5-15519 detects FGB, which has a predicted molecular weight of approximately 52 kDa.
Target Information
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains.
Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the main component of blood clots.
Various fibrinogen and fibrin cleavage products regulate cell adhesion and spreading, exhibit vasoconstrictor and chemotactic activities, and act as mitogens for several cell types.
Mutations in the FIBB gene can lead to afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia, and thrombotic disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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