Thermo Fisher Scientific MUSK Monoclonal Antibody (10A4)
Human MUSK 단백질에 특이적인 Mouse monoclonal antibody (Clone 10A4). WB, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. Unconjugated 형태로 제공되며, 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10A4 |
| Immunogen | Purified recombinant extracellular fragment of human MUSK (aa24–209) fused with hIgGFc tag expressed in HEK293 cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C for short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10984848 |
Product Specific Information
MA5-15518 targets MUSK in indirect ELISA, IF, and IHC applications and shows reactivity with human samples.
The immunogen is a purified recombinant extracellular fragment of human MUSK (aa24–209) fused with an hIgGFc tag expressed in HEK293 cells.
MA5-15518 detects MUSK, which has a predicted molecular weight of approximately 97 kDa.
Target Information
MUSK plays an important and selective role in skeletal muscle development and function through postsynaptic differentiation and formation of end-plate bands in cooperation with Rapsyn.
It is part of the agrin signaling complex and contributes to the development and maintenance of the neuromuscular junction.
Receptor tyrosine kinase activity is regulated by ligand binding to the extracellular active site of the receptor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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