Thermo Fisher Scientific PSA Monoclonal Antibody (EP1588Y)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:10-1:100

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

-

Immunocytochemistry (ICC/IF)

1:10-1:200

View 1 publication 1 publication

Product Specifications

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Monoclonal

Type

Antibody

Clone

EP1588Y

Immunogen

A synthetic peptide corresponding to residues near the C-terminus of human PSA if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PSA,uniProtId:P07288-1,ncbiNodeId:9606,antigenRange:261,antigenLength:261,antigenImageFileName:MA5-14470_PSA_P07288-1_Rabbit.svg,antigenImageFileNamePDP:MA5-14470_PSA_P07288-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Conc. Not Determined

Storage conditions

4° C

Shipping conditions

Wet ice

RRID

AB_10985812

Product Specific Information

MA5-14470 targets Prostate Specific Antigen in IHC (P), ICC/IF and WB applications and shows reactivity with Human samples, however this antibody is not recommended for human colon and mouse prostate tissue sections. This antibody does not react with rat tissue in Western blot applications.

The MA5-14470 immunogen is a synthetic peptide corresponding to residues near the C-terminus of human PSA.

Target Information

PSA is a chymotrypsin-like serine protease (kallikrein family) produced by the prostate epithelium, and is abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.