Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI1A7), TrueMAB
인간 TMEM173 단백질을 인식하는 단클론 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 마우스 IgG2b 아이소타입이며, 액상 형태로 제공됩니다. 고순도 친화 크로마토그래피 정제 제품으로 안정적인 신호 검출이 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A7 |
| Immunogen | Full length human recombinant protein of human TMEM173 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
STING is a 379 amino acid signaling protein that plays a key role in innate immune signaling. It activates NF-kappa-B and IRF3 transcription pathways to induce type I interferon (IFN-α and IFN-β) expression, promoting antiviral responses. STING may also function as a translocon, influencing interferon induction and apoptotic signaling via MHC-II association. It is localized in the endoplasmic reticulum membrane, cell membrane, and outer mitochondrial membrane, and is broadly expressed across various tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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