Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI1G5), TrueMAB
인간 TMEM173(STING) 단백질을 인식하는 마우스 단클론 항체로 Western blot과 유세포분석에 적합. TrueMAB 포맷으로 높은 특이성과 재현성을 제공. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G5 |
| Immunogen | Full length human recombinant protein of human TMEM173 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
STING (TMEM173) is a 379-amino-acid signaling protein that plays a key role in innate immune signaling. It activates NF-kappa-B and IRF3 transcription pathways to induce type I interferon (IFN-α, IFN-β) expression, establishing a potent antiviral state. STING may also have translocon function and is involved in apoptotic signaling through association with MHC-II, aiding detection of intracellular viral RNA and DNA. It mediates death signaling via ERK pathway activation and is localized to the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane. STING is ubiquitously expressed across most tissues.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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