Thermo Fisher Scientific TAP1 Polyclonal Antibody
Human TAP1 단백질의 C-말단 영역을 인식하는 Rabbit Polyclonal Antibody. Western blot, ELISA, Flow Cytometry, Immunoprecipitation에 사용 가능. 1 mg/mL 농도의 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:1,000 | |
| Flow Cytometry (Flow) | Assay-dependent | |
| ELISA | 1:10,000 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | TAP1 peptide corresponding to the C-terminal of the human protein conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2 |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2271484 |
Product Specific Information
- In Western blot, this antibody detects a band at approximately 72 kDa.
- Rabbit anti-Human TAP1 antibody detects an epitope within the C-terminal region of human TAP1, also known as transporter associated with antigen processing 1.
Target Information
The membrane-associated protein encoded by this gene is a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
This protein belongs to the MDR/TAP subfamily, which is involved in multidrug resistance. The encoded protein pumps degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble.
Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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