Thermo Fisher Scientific PPAR delta Polyclonal Antibody
PPAR delta 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 ELISA에 적합합니다. Human과 Mouse에 반응하며, Affinity chromatography로 정제되었습니다. PBS buffer에 보관하며 장기 보관 시 -20°C에서 보관 권장됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PPAR delta Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1:2,000–1:8,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1–14 of mouse PPAR delta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2165893 |
Product Specific Information
- Predicted to react with chimpanzee, mouse, rabbit, and rat based on sequence homology.
- In Western blots, a band at approximately 55 kDa is detected from heart whole cell lysates.
- Rabbit anti-PPAR delta antibody detects peroxisome proliferator-activated receptor delta (PPARD), a member of the nuclear hormone receptor subfamily.
Target Information
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. PPARs are nuclear hormone receptors that bind peroxisome proliferators and regulate peroxisome number and size in cells. They mediate various biological processes and may be involved in chronic diseases such as diabetes, obesity, atherosclerosis, and cancer.
PPAR delta acts as an inhibitor of ligand-induced transcription activity of PPAR alpha and gamma, functioning as an integrator of transcription repression and nuclear receptor signaling. Its expression is elevated in colorectal cancer cells and can be repressed by the tumor suppressor protein APC. Knockout studies in mice suggest roles in myelination, lipid metabolism, and epidermal cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.