Thermo Fisher Scientific Human S100B Recombinant Protein
Recombinant human S100B protein with N-terminal His-tag. Suitable as a positive control in immunological assays. >95% purity, expressed in E. coli. Supplied in PBS with 50% glycerol. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Control (Ctrl)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Amino acids Ser2–Glu92 containing an N-terminal His-tag |
| Tag | His-tag |
| Molecular Weight | 14.7 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
RP-75721 contains purified recombinant human S100 beta chain protein with an N-terminal hexahistidine tag.
This product may be used as a positive control in various immunological assays.
Target Information
S100B is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. These proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and regulate several cellular processes such as cell cycle progression and differentiation.
S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca²⁺ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly.
Chromosomal rearrangements and altered expression of this gene have been implicated in diseases including Alzheimer’s disease, Down’s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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