Thermo Fisher Scientific Human S100B Recombinant Protein
Recombinant human S100B 단백질로, E. coli에서 발현된 N-말단 His-tag 단백질입니다. Western blot 등 면역학적 분석의 양성 대조군으로 사용됩니다. 95% 이상 순도의 액상 형태이며, PBS(glycerol 포함)로 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Assay-dependent
Control (Ctrl)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Amino acids Ser2–Glu92 containing an N-terminal His-tag |
| Tag | His-tag |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
This product contains purified recombinant human S100 beta chain protein with an N-terminal hexahistidine tag.
It may be used as a positive control in various immunological assays.
Target Information
S100B is a member of the S100 family of proteins containing two EF-hand calcium-binding motifs. These proteins are localized in the cytoplasm and/or nucleus of various cells and are involved in regulating multiple cellular processes such as cell cycle progression and differentiation.
S100B may function in:
- Neurite extension
- Melanoma cell proliferation
- Stimulation of Ca²⁺ fluxes
- Inhibition of PKC-mediated phosphorylation
- Astrocytosis and axonal proliferation
- Inhibition of microtubule assembly
Chromosomal rearrangements and altered expression of this gene have been associated with diseases such as Alzheimer’s disease, Down’s syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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