Thermo Fisher Scientific PSMD11 Polyclonal Antibody
Thermo Fisher Scientific의 PSMD11 Polyclonal Antibody는 인간 및 생쥐에 반응하며 Western blot과 IHC(P) 분석에 적합합니다. KLH 결합 합성 펩타이드로 면역화된 토끼 IgG 폴리클로날 항체로, 액상 형태이며 PBS 버퍼에 보관됩니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 288–317 from the C-terminal region of human PSMD11 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2172966 |
Product Specific Information
This antibody is predicted to react with bovine and rat based on sequence homology.
Target Information
The 26S proteasome (PSMD11) is a multicatalytic proteinase complex with a highly ordered structure composed of two complexes: a 20S core and a 19S regulator.
- The 20S core consists of four rings of 28 non-identical subunits (two rings of seven alpha subunits and two rings of seven beta subunits).
- The 19S regulator includes a base (six ATPase and two non-ATPase subunits) and a lid (up to ten non-ATPase subunits).
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
A modified proteasome, the immunoproteasome, plays an essential role in processing class I MHC peptides.
PSMD11 is a non-ATPase subunit of the 19S regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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