Thermo Fisher Scientific Human APC7 Synthetic Peptide
인간 APC7 단백질의 C-말단 18개 아미노산 서열에 해당하는 합성 펩타이드. 폴리클로날 항체 PA5-20948의 블로킹 펩타이드로 사용 가능. 세포주기 관련 APC/C 복합체 연구에 적합. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 18 amino acids near the carboxy terminus of human APC7.
PEP-1062 can be used as a blocking peptide with polyclonal antibody PA5-20948.
Target Information
Cell cycle–regulated protein ubiquitination and degradation within subcellular domains is essential for normal mitosis progression.
APC7 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle–regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase.
APC/C mediates degradation of anaphase inhibitors, mitotic cyclins, and spindle-associated proteins, ensuring proper mitotic sequence.
APC7 is required for proper protein ubiquitination function of APC/C and interaction with various transcription coactivators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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