Thermo Fisher Scientific Human APC5 Synthetic Peptide
인간 APC5 단백질의 중심부 17개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20946의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며, PBS(pH 7.2, 0.1% BSA) 완충액에 0.02% sodium azide 포함. 연구용으로만 사용.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 17 amino acids near the center of human APC5.
PEP-1060 can be used as a blocking peptide with polyclonal antibody PA5-20946.
Target Information
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination.
The encoded protein is required for the proper ubiquitination function of APC/C and for interaction with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation.
Multiple transcript variants encoding different isoforms have been found for this gene, resulting in translation initiation at a downstream AUG and a shorter protein compared to isoform a.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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