Thermo Fisher Scientific CD267 (TACI) Polyclonal Antibody, Biotin, PeproTech

Thermo Fisher Scientific CD267 (TACI) Polyclonal Antibody, Biotin, PeproTech

Applications and Tested Dilution

Product Specifications

Product Specific Information

AA Sequence of recombinant protein:
SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV

Preparation:
Produced from sera of goats immunized with highly pure Recombinant Human TACI. Anti-Human TACI-specific antibody was purified by affinity chromatography and then biotinylated.

Sandwich ELISA:
To detect hTACI by sandwich ELISA (using 100 µL/well antibody solution), a concentration of 0.25–1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human TACI (500-P166G) as a capture antibody, allows detection of at least 0.2–0.4 ng/well of Recombinant hTACI.

Western Blot:
To detect hTACI by Western Blot analysis, this antibody can be used at 0.1–0.2 µg/mL. Used with compatible secondary reagents, detection limit for Recombinant hTACI is 1.5–3.0 ng/lane under reducing or non-reducing conditions.

Packaging:
500-P166GBT-1MG is provided as 2 × 500 µg.

Target Information

Members of the TNF superfamily regulate immune responses and induce apoptosis. Two novel members, BAFF (BLyS/TALL-1/THANK/zTNF4) and APRIL (TALL-2), were identified.
BAFF acts as a B cell activator, inducing proliferation and immunoglobulin secretion. APRIL regulates cell growth.
Three receptors—BCMA, TACI, and BAFF-R—bind BAFF and APRIL. TACI and its ligands regulate humoral immune responses, activate NF-κB and c-Jun N-terminal kinase, and are involved in B cell–associated autoimmune diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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