Thermo Fisher Scientific CD267 (TACI) Polyclonal Antibody, Biotin, PeproTech
Human TACI 단백질을 표적으로 하는 Biotin 결합 염소 유래 폴리클로날 항체로, Western blot, ELISA, IHC 등 다양한 응용에 적합. 고순도 항원 친화 크로마토그래피 정제 제품으로 연구용 면역 분석에 사용.
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Thermo Fisher Scientific CD267 (TACI) Polyclonal Antibody, Biotin, PeproTech
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL | - |
| Immunohistochemistry (IHC) | - | 1 publication |
| Flow Cytometry (Flow) | - | 1 publication |
| ELISA | 0.25–1.0 µg/mL | 1 publication |
| In vitro Assay (IV) | - | 2 publications |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived Recombinant Human TACI (17.8 kDa) |
| Conjugate | Biotin |
| Form | Lyophilized |
| Concentration | 0.1–1.0 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
| RRID | AB_2929592 |
Product Specific Information
AA Sequence of recombinant protein:
SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV
Preparation:
Produced from sera of goats immunized with highly pure Recombinant Human TACI. Anti-Human TACI-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA:
To detect hTACI by sandwich ELISA (using 100 µL/well antibody solution), a concentration of 0.25–1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human TACI (500-P166G) as a capture antibody, allows detection of at least 0.2–0.4 ng/well of Recombinant hTACI.
Western Blot:
To detect hTACI by Western Blot analysis, this antibody can be used at 0.1–0.2 µg/mL. Used with compatible secondary reagents, detection limit for Recombinant hTACI is 1.5–3.0 ng/lane under reducing or non-reducing conditions.
Packaging:
500-P166GBT-1MG is provided as 2 × 500 µg.
Target Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. Two novel members, BAFF (BLyS/TALL-1/THANK/zTNF4) and APRIL (TALL-2), were identified.
BAFF acts as a B cell activator, inducing proliferation and immunoglobulin secretion. APRIL regulates cell growth.
Three receptors—BCMA, TACI, and BAFF-R—bind BAFF and APRIL. TACI and its ligands regulate humoral immune responses, activate NF-κB and c-Jun N-terminal kinase, and are involved in B cell–associated autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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