Thermo Fisher Scientific Rab3-GAP1 Polyclonal Antibody
Rabbit 유래 Rab3-GAP1 폴리클로날 항체로 Western blot 및 Immunoprecipitation에 적합. 인간 RAB3GAP1 단백질의 575–625번 잔기 영역을 면역원으로 사용. 액상 형태, 0.20 mg/mL 농도, 4°C 보관. 뇌 및 신경 발달 관련 연구에 활용 가능.
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Thermo Fisher Scientific Rab3-GAP1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 and 625 of Human RAB3 GTPase activating protein subunit 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
RAB3GAP1 is a 981 amino acid protein belonging to the Rab3-GAP catalytic subunit family. Rab3 GAP p130 converts active RAB3-GTP to the inactive form RAB3-GDP and is essential for normal eye and brain development.
Defects in Rab3 GAP p130 cause Warburg micro syndrome 1 (WARBM1), a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia.
Rab3 GAP p130 may participate in neurodevelopmental processes such as proliferation, migration, differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(이미지 파일: A302-114A-M_RAB3GAP1_Q15042-1_Rabbit.svg, A302-114A-M_RAB3GAP1_Q15042-1_Rabbit_PDP.jpeg)
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