Thermo Fisher Scientific Rab3-GAP1 Polyclonal Antibody
Rab3-GAP1 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간 시료에 반응합니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 350 and 400 of Human RAB3 GTPase activating protein subunit 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
RAB3GAP1 is a 981 amino acid protein belonging to the Rab3-GAP catalytic subunit family. Rab3 GAP p130 converts active RAB3-GTP to inactive RAB3-GDP and is essential for normal eye and brain development. Defects in Rab3 GAP p130 cause Warburg micro syndrome 1 (WARBM1), a severe autosomal recessive disorder characterized by eye and CNS developmental abnormalities and microgenitalia. Rab3 GAP p130 may participate in neurodevelopmental processes such as proliferation, migration, differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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