Thermo Fisher Scientific Phospho-NFkB p65 (Ser536) Polyclonal Antibody
NFkB p65 (Ser536) 인산화 부위를 인식하는 폴리클로날 항체로, Western blot에 적합. Rabbit IgG 호스트에서 생산되었으며, 비결합형 액상 형태. 세포 신호전달 및 NF-κB 경로 연구용으로 적합. -20°C 보관, 연구용 전용.
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Applications
- Western Blot (WB): 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of human NFkB that contains serine 536. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice (domestic); Wet or Dry ice (international) |
| RRID | AB_2533729 |
Target Information
Nuclear factor kB p65 (NF-kB p65) is encoded by the RELA gene and is present on chromosome 11 in humans. NF-kB p65, also known as RelA, belongs to the Rel family of proteins and forms heterodimers with subunits p50 or p52. Upon TNF alpha receptor activation, IKK phosphorylates IκB, leading to its proteasomal degradation and subsequent NF-kB activation. NF-kB p65 plays a critical role in transcription of the immunoglobulin kappa gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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