
Thermo Fisher Scientific IL-1 beta Recombinant Superclonal Antibody (14HCLC)
Rat IL-1 beta를 인식하는 Recombinant Superclonal™ Rabbit 항체로, 높은 특이성과 재현성을 제공합니다. Western blot에 적합하며, polyclonal의 민감도와 monoclonal의 일관성을 결합하였습니다. 단백질 A로 정제된 액상 항체로 4°C 단기 보관 가능합니다.
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Applications
- Western Blot (WB): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Superclonal |
| Type | Antibody |
| Clone | 14HCLC |
| Immunogen | Recombinant protein corresponding to amino acids 1–152 of rat interleukin-1 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532624 |
Product Specific Information
Recombinant rabbit Superclonal™ antibodies are composed of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies. Each lot is produced with a defined mixture of light and heavy chains, ensuring batch-to-batch consistency and eliminating biological variability.
This product was formerly known as “Recombinant Polyclonal Antibody” and has been rebranded as “Recombinant Superclonal™ Antibody” with no change in performance or composition.
Target Information
Interleukin-1 beta (IL-1β) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. It is synthesized as a 31 kDa inactive pro-form and activated by inflammasome-mediated cleavage into a 17 kDa mature form. IL-1β plays a central role in innate immune responses by inducing other proinflammatory cytokines and acute-phase reactions.
It signals through IL-1RI and IL-1RII receptors and is regulated by IL-1 Receptor Antagonist (IL-1RA). Elevated IL-1β levels are associated with various chronic inflammatory diseases, making IL-1β a key target for research in inflammation and immune regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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